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Nausea and diarrhea Skin rash Hair thinning or loss which is reversible when the medication is stopped.

Interstitial lung disease and worsening of pre-existing interstitial lung disease have been reported during treatment with ARAVA and has been associated with fatal outcomes [see ADVERSE REACTIONS ]. The risk of ARAVA-associated interstitial lung disease is increased in patients with a history of interstitial lung disease. Interstitial lung disease is a potentially fatal disorder that may occur acutely at any time during therapy and has a variable clinical presentation. New onset or worsening pulmonary symptoms.such as cough and dyspnea.with or without associated fever.may be a reason for discontinuation of ARAVA therapy and for further investigation as appropriate. If discontinuation of ARAVA is necessary.consider performing an accelerated drug elimination procedure [see Procedure for Accelerated Elimination of ARAVA and its Active Metabolite ].

CONTRAINDICATIONS AND WARNINGS Pregnancy Leflunomide is contraindicated in pregnant women.or women of childbearing potential who are not using reliable contraception. Pregnancy must be excluded before the start of treatment with Caravan sales. Pregnancy must be avoided during Leflunomide treatment and during caravan sales accelerated drug elimination procedure after Leflunomide treatment. Leflunomide should be stopped and an accelerated drug elimination procedure should be started if the patient becomes pregnant.

After treatment is stopped.a different drug (cholestyramine) may be given as directed to help remove leflunomide from your body. This procedure is used if you need a rapid removal of the drug from your system (e.g..a female/male planning to have children.a person suffering from severe side effects). Without the procedure.the drug may stay in your body for up to 2 years. Consult caravan sales doctor or pharmacist for more details.

This medication must not be used during pregnancy. It may harm an unborn baby. Before starting this medication.women of childbearing age must have a negative pregnancy test before starting this medication. Men and women must use effective forms of birth control (e.g..condoms and birth control pills) while taking this medication. Consult your doctor for more details and to discuss reliable forms of birth control. (See also Warning section.)

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