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Shah also said physicians prefer ibuprofen more than celebrex and vioxx combined.

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Carefully consider the potential benefits and risks of CELEBREX and other treatment options before deciding to use CELEBREXUse the lowest effective dosage for the shortest duration consistent with individual patient treatment goalssee WARNINGS AND PRECAUTIONS

In controlled clinical trialselevated BUN occurred more frequently in patients receiving CELEBREX compared with patients on placeboThis laboratory abnormality was also seen in patients who received comparator NSAIDs in these studiesThe clinical significance of this abnormality has not been established.

Inform patients of the signs of an anaphylactic reactione.gdifficulty breathingswelling of the face or throatInstruct patients to seek immediate emergency help if these occursee CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS

A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polypsseverepotentially fatal bronchospasmand/or intolerance to aspirin and other NSAIDsBecause cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patientsCELEBREX is contraindicated in patients with this form of aspirin sensitivitysee CONTRAINDICATIONSWhen CELEBREX is used in patients with preexisting asthmawithout known aspirin sensitivitymonitor patients for changes in the signs and symptoms of asthma.

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shah also said physicians prefer ibuprofen more than celebrex and vioxx combined.